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Case Reports
. 2004 Feb;75(2):92-5.
doi: 10.1002/ajh.10456.

Chronic myeloid leukemia with an e13a3 BCR-ABL fusion: benign course responsive to imatinib with an RT-PCR advisory

David S Snyder  1 , Ross McMahon, Sandra R Cohen, Marilyn L Slovak
Affiliations
Free article
Case Reports

Chronic myeloid leukemia with an e13a3 BCR-ABL fusion: benign course responsive to imatinib with an RT-PCR advisory

David S Snyder et al. Am J Hematol. 2004 Feb.
Free article

Abstract

A case of a patient with chronic myeloid leukemia whose cells expressed an e13a3 (b2a3) variant BCR-ABL p210 mRNA is presented. The variant splice was detected by a qualitative reverse transcriptase polymerase chain reaction using primers complementary to BCR exon 13 (b2) and ABL exon 3 (a3). The patient responded well to imatinib and achieved a complete cytogenetic response.

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