Review
doi: 10.1016/0168-9525(92)90278-c.
Insertional mutation of 'classical' and novel genes in transgenic mice
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- PMID: 1475845
- DOI: 10.1016/0168-9525(92)90278-c
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Review
Insertional mutation of 'classical' and novel genes in transgenic mice
Trends Genet.
1992 Oct.
Free article
Abstract
Approximately 5% of established transgenic lines carry insertional mutations. The mutated genes may be directly isolated using the transgene DNA as a molecular probe. These mutants provide useful models of human inherited disorders and developmental abnormalities.
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