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Review
. 1992 Oct;8(10):341-4.
doi: 10.1016/0168-9525(92)90278-c.

Insertional mutation of 'classical' and novel genes in transgenic mice

M H Meisler  1
Affiliations
Free article
Review

Insertional mutation of 'classical' and novel genes in transgenic mice

M H Meisler. Trends Genet. 1992 Oct.
Free article

Abstract

Approximately 5% of established transgenic lines carry insertional mutations. The mutated genes may be directly isolated using the transgene DNA as a molecular probe. These mutants provide useful models of human inherited disorders and developmental abnormalities.

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