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. 1992 Dec;58(12):3879-82.
doi: 10.1128/aem.58.12.3879-3882.1992.

Biphenomycin A production by a mixed culture

M Ezaki  1 , M Iwami, M Yamashita, T Komori, K Umehara, H Imanaka
Affiliations

Biphenomycin A production by a mixed culture

M Ezaki et al. Appl Environ Microbiol. 1992 Dec.

Abstract

Production of biphenomycin A by Streptomyces griseorubiginosus 43708 was stimulated by a mixed culture with a partner strain, Pseudomonas maltophilia 1928. This stimulatory effect on biphenomycin A accumulation by the mixed culture was caused by the enzyme activity which strain 1928 possessed. It is suggested that in a mixed culture strain 43708 produces a precursor of biphenomycin A in culture broth and that strain 1928 converts the precursor to biphenomycin A.

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