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Review
. 2004 Feb;39(2):291-4.
doi: 10.1002/hep.20069.

Severe acute respiratory syndrome and the liver

Review

Severe acute respiratory syndrome and the liver

Atul Humar et al. Hepatology. 2004 Feb.
No abstract available

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Figures

Figure 1
Figure 1
Structure of a coronavirus. (A) Schematic of the coronavirus MHV showing structural proteins and the genomic RNA. (B) Electron micrograph of the SCoV recovered from lung tissue from a patient who died of SARS.
Figure 2
Figure 2
Liver histologic analysis in susceptible mice after MHV‐3 infection. (A) Areas of focal hepatic necrosis with polymorphonuclear infiltrates (arrow; original magnification, ×350). (B) Confluent hepatic necrosis with mononuclear cell infiltrates (arrow; original magnification, ×350).
Figure 3
Figure 3
Assays for detection of coronavirus infection (MHV). (A) Plaque assay with fusion of cells (syncytia) on a monolayer of L2 cells stained with crystal violet. (B) Electron micrograph of liver at 3 days after infection showing typical MHV virions in a hepatocyte (arrow). The virions are round, mildly pleomorphic (100–120 nm), and show surface membrane thickening indicative of the corona peplomer structure.

Comment on

References

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