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Comment
. 2004 Feb 17;101(7):1795-6.
doi: 10.1073/pnas.0400237101. Epub 2004 Feb 9.

Slow-wave sleep, acetylcholine, and memory consolidation

Ann E Power  1
Affiliations
Comment

Slow-wave sleep, acetylcholine, and memory consolidation

Ann E Power. Proc Natl Acad Sci U S A. .

Erratum in

  • Proc Natl Acad Sci U S A. 2004 Mar 23;101(12):4331
No abstract available

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Figures

Fig. 1.
Fig. 1.
During waking, elevated acetylcholine (ACh) release from the cholinergic basal forebrain may enhance memory acquisition and consolidation (Left). The SWS release from ACh-mediated suppression of hippocampal feedback to the neocortex may then provide a privileged window for hippocampus to neocortex information transfer of memory traces recently encoded in the hippocampus (Center). A shift back to elevated ACh levels during REM sleep may facilitate savings in cortical circuits of information relayed during SWS (Right). Cortical cell groups send information to hippocampal circuitry, the dentate gyrus (DG) and area CA3, by means of the entorhinal cortex (EC). Hippocampal feedback signals to cortices are relayed back through the EC from area CA1.
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