Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1950 Nov 1;92(5):499-505.
doi: 10.1084/jem.92.5.499.

Immunological reactions of the Coxsackie viruses. III. Cross-protection tests in infant mice born of vaccinated mothers; transfer of immunity through the milk

J L MELNICK, N A CLARKE, L M KRAFT

Immunological reactions of the Coxsackie viruses. III. Cross-protection tests in infant mice born of vaccinated mothers; transfer of immunity through the milk

J L MELNICK et al. J Exp Med. .

Abstract

Maternal antibodies to the Coxsackie viruses (C virus) are conveyed to newborn mice through the colostrum and milk. of vaccinated mothers. No evidence for or against placental transmission of immunity was obtained. The immunity conferred on the young is type-specific. Immunity may be conferred to infants born of non-immune mice by allowing a suckling period of 24 to 48 hours with an immune mother. Immunity appears to be transferred through the milk for the duration of lactation. Strains of C virus can be typed by challenging infant mice born to mothers vaccinated with known types according to the outline presented above. Complement-fixing antibodies are also transferred from vaccinated mother mice to their offspring.

PubMed Disclaimer

References

    1. J Exp Med. 1930 Sep 30;52(4):457-64 - PubMed
    1. Am J Hyg. 1949 Sep;50(2):200 6 - PubMed
    1. J Exp Med. 1950 Nov 1;92(5):463-82 - PubMed
    1. J Exp Med. 1950 Nov 1;92(5):483-97 - PubMed
    1. Acta Pathol Microbiol Scand. 1949;26(1):175-7 - PubMed