Review
doi: 10.1016/0378-1135(92)90054-w.
The molecular biology of the porcine paramyxovirus LPMV
Affiliations
- PMID: 1481359
- DOI: 10.1016/0378-1135(92)90054-w
Item in Clipboard
Review
The molecular biology of the porcine paramyxovirus LPMV
Vet Microbiol.
1992 Nov.
Abstract
Protein and genomic studies of a previously uncharacterized porcine paramyxovirus (designated LPMV) confirmed that it was a member of the paramyxovirus genus. The nucleotide sequences and deduced amino acids of the complete P-gene, M-gene, F-gene and HN-gene as well as the intergenic sequences have been determined. Comparative sequence analysis of the M-gene of LPMV revealed the closest relationship of LPMV was to human mumps virus with a homology of 46% and 55% at the amino acid and nucleotide levels respectively. The P-gene of LPMV is transcribed to V protein mRNA and by editing of the gene to the P protein mRNA. The LPMV P-gene has the coding capacity for an additional protein of 126 amino acids, a C protein.
Similar articles
-
Identification of the porcine paramyxovirus LPMV matrix protein gene: comparative sequence analysis with other paramyxoviruses.J Gen Virol. 1991 May;72 ( Pt 5):1045-50. doi: 10.1099/0022-1317-72-5-1045. J Gen Virol. 1991. PMID: 2033388
-
The haemagglutinin-neuraminidase glycoprotein of the porcine paramyxovirus LPMV: comparison with other paramyxoviruses revealed the closest relationship to simian virus 5 and mumps virus.Arch Virol. 1992;122(3-4):331-40. doi: 10.1007/BF01317194. Arch Virol. 1992. PMID: 1731697
-
The P gene of the porcine paramyxovirus LPMV encodes three possible polypeptides P, V and C: the P protein mRNA is edited.J Gen Virol. 1992 May;73 ( Pt 5):1195-200. doi: 10.1099/0022-1317-73-5-1195. J Gen Virol. 1992. PMID: 1588322
-
Avian Paramyxoviridae--recent developments.Vet Microbiol. 1990 Jun;23(1-4):103-14. doi: 10.1016/0378-1135(90)90140-q. Vet Microbiol. 1990. PMID: 2205966 Review.
-
Biological properties of phocine distemper virus and canine distemper virus.APMIS Suppl. 1993;36:1-51. APMIS Suppl. 1993. PMID: 8268007 Review.
Cited by
-
Full-length genome sequence and genetic relationship of two paramyxoviruses isolated from bat and pigs in the Americas.Arch Virol. 2007;152(7):1259-71. doi: 10.1007/s00705-007-0959-4. Epub 2007 Mar 26. Arch Virol. 2007. PMID: 17385069 Free PMC article.
-
Development of a real-time RT-PCR method for detection of porcine rubulavirus (PoRV-LPMV).J Virol Methods. 2013 Apr;189(1):1-6. doi: 10.1016/j.jviromet.2012.12.009. Epub 2013 Jan 7. J Virol Methods. 2013. PMID: 23305816 Free PMC article.
-
Analysis of the fusion protein gene of the porcine rubulavirus LPMV: comparative analysis of paramyxovirus F proteins.Virus Genes. 1997;14(1):55-61. doi: 10.1023/a:1007987407250. Virus Genes. 1997. PMID: 9208455
-
Genetic and antigenic changes in porcine rubulavirus.Can J Vet Res. 2012 Jan;76(1):33-7. Can J Vet Res. 2012. PMID: 22754092 Free PMC article.
-
La Piedad Michoacán Mexico Virus V protein antagonizes type I interferon response by binding STAT2 protein and preventing STATs nuclear translocation.Virus Res. 2016 Feb 2;213:11-22. doi: 10.1016/j.virusres.2015.10.027. Epub 2015 Nov 3. Virus Res. 2016. PMID: 26546155 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
