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. 1978 Mar 1;169(3):559-65.
doi: 10.1042/bj1690559.

Gliding edge dislocations in proteins as a mechanism for active ion transport

H D Chandler, C J Woolf, H R Hepburn

Gliding edge dislocations in proteins as a mechanism for active ion transport

H D Chandler et al. Biochem J. .

Abstract

A mechanism for the translocation of ions across biological membranes is proposed in which transconformational changes occur in the membrane-bound ion pump. In particular, it is suggested that such conformational changes are effected by means of the propagation of crystal defects in the form of edge-dislocation glide.

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