Review
Emerging treatments: replacement therapy with choline or lecithin in neurological diseases
- PMID: 148319
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Review
Emerging treatments: replacement therapy with choline or lecithin in neurological diseases
Can J Neurol Sci.
1978 Feb.
Abstract
This review evaluates the theoretical background and experimental data behind a new development: the replacement therapy of deficient central cholinergic systems with the dietary precursors choline or lecithin. Cholinergic deficiency states are possibly present in five neurological entities: Huntington's chorea, Tardive Dyskinesia, Gilles de la Tourette's disease, Friedreich's ataxia and pre-senile dementia. Preliminary data from various laboratories, including our own, in each of these disorders indicate that some clinical improvement can occasionally be seen, and that this approach deserves further investigation.
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