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. 1992;30(2):75-8.

Disturbances of mineral metabolism in teeth of rats receiving corticosteroids for 3 generations

R Pawlicki  1 , Z Knychalska-Karwin, D Stankiewicz, K Jakób-Dolezal, T Karwan
Affiliations
  • PMID: 1483537

Disturbances of mineral metabolism in teeth of rats receiving corticosteroids for 3 generations

R Pawlicki et al. Folia Histochem Cytobiol. 1992.

Abstract

Distribution of calcium and phosphorus was investigated with quantitative and qualitative methods in teeth of rats chronically treated with low doses of corticosteroids for 3 generations. In animals from 2nd and 3rd generation, scanning electron microscopy revealed focal lesions in enamel and dentin. The disturbances of the mineral metabolism in teeth of corticosteroid-treated rats were also reflected by abnormal calcium and phosphorus content in enamel and dentin, as assessed by X-ray microanalysis.

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