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Comparative Study
. 1992 Dec;56(2):357-60.
doi: 10.1016/0166-6851(92)90188-p.

Cloning and sequencing of an hsp70 gene of Schistosoma mansoni

S Neumann  1 , E Ziv, F Lantner, I Schechter
Affiliations
Comparative Study

Cloning and sequencing of an hsp70 gene of Schistosoma mansoni

S Neumann et al. Mol Biochem Parasitol. 1992 Dec.

Abstract

Schistosomes have a complex life cycle (vertebrate and molluscan hosts as well as larvae living freely in water) in which they are exposed to different environments and temperatures (20 degrees C - 37 degrees C). Since heat shock genes are activated in response to stress and during development [1], it is of interest to study the hsp70 gene family in schistosome. To approach this issue we have isolated from Schistosoma mansoni a genomic clone containing the complete coding region of hsp70 and the 5' flanking DNA with transcription regulatory elements including HSE (heat shock element) sequences.

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