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Case Reports
. 1992;242(2-3):69-71.
doi: 10.1007/BF02191548.

Marchiafava-Bignami disease. A case studied by structural and functional brain imaging

T Humbert  1 , P De Guilhermier, C Maktouf, G Grasset, F M Lopez, P Chabrand
Affiliations
Case Reports

Marchiafava-Bignami disease. A case studied by structural and functional brain imaging

T Humbert et al. Eur Arch Psychiatry Clin Neurosci. 1992.

Abstract

Marchiafava-Bignami disease (MBD) is a rare complication of chronic alcoholism. The clinical features, X-ray, CT and MRI findings are well documented. However, functional brain imaging has not been used in cases of MBD. We used single-photon emission computed tomography (SPECT) to monitor the regional cerebral blood flow in a patient suffering from a acute form of MBD, from which he subsequently recovered. Several abnormalities were found. A more frequent use of functional brain imaging in MBD could improve our knowledge of pathogenesis and prognosis for MBD.

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