Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1992;2(4):283-314.

The nuclear serine/threonine protein kinase DNA-PK

C W Anderson  1 , S P Lees-Miller
Affiliations
  • PMID: 1486241
Review

The nuclear serine/threonine protein kinase DNA-PK

C W Anderson et al. Crit Rev Eukaryot Gene Expr. 1992.

Abstract

The DNA-activated protein kinase (DNA-PK) is a nuclear serine/threonine protein kinase that phosphorylates DNA-binding proteins, including several transcription factors. DNA-PK is one of a very few enzymes known to be regulated through interaction with DNA that does not have DNA as a template or substrate. We suggest that DNA-PK may function in cell homeostasis, in part through the modulation of transcriptional activity.

PubMed Disclaimer

Publication types

MeSH terms

LinkOut - more resources