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Review
. 1992 Dec;21(4):833-58.

Regulation and dysregulation of the hypothalamic-pituitary-adrenal axis. The corticotropin-releasing hormone perspective

G P Chrousos  1
Affiliations
  • PMID: 1486878
Review

Regulation and dysregulation of the hypothalamic-pituitary-adrenal axis. The corticotropin-releasing hormone perspective

G P Chrousos. Endocrinol Metab Clin North Am. 1992 Dec.

Abstract

This article is an up-to-date review of the impact that the discovery of corticotropin-releasing hormone (CRH) has had on basic science and clinical medicine. It discusses hypothalamic CRH, placental CRH, immune CRH, and hypothalamic and immune CRH. Clinical studies in normal and disease states and synthesis and future directions also are presented.

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