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Case Reports
. 1978 May 5;378(1):17-22.
doi: 10.1007/BF00427182.

Jejunal endocrine tumor composed of somatostatin and gastrin cells and associated with duodenal ulcer disease

Case Reports

Jejunal endocrine tumor composed of somatostatin and gastrin cells and associated with duodenal ulcer disease

J Alumets et al. Virchows Arch A Pathol Anat Histol. .

Abstract

A case of malignant endocrine tumour of the jejunum, associated with severe duodenal ulcer is described. The tumour and a local metastasis were examined by immunohistochemistry and found to contain abundant somatostatin-immunoreactive cells together with less numerous cells displaying gastrin immunoreactivity. This is to our knowledge the first case of intestinal somatostatinoma. The presence of gastrin cells in the tumour may explain the ulcer diathesis.

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