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. 1978 May;5(5):421-4.
doi: 10.1111/j.1365-2125.1978.tb01648.x.

Effect of dopamine on airways conductance in normals and extrinsic asthmatics

N C Thomson, K R Patel

Effect of dopamine on airways conductance in normals and extrinsic asthmatics

N C Thomson et al. Br J Clin Pharmacol. 1978 May.

Abstract

1 Specific conductance was measured before and after infused and/or inhaled dopamine in nine normal subjects and twelve patients with extrinsic bronchial asthma. 2 There was no significant change in conductance in either group. 3 The alpha-adrenergic receptor antagonist thymoxamine infused in combination with dopamine had no significant effect on conductance in three asthmatics. 4 It is concluded that dopamine has no acute effect on airways resistance and that specific dopamine receptors are unlikely to exist in human airways.

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