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Comparative Study
. 1992 Nov;36(11):2533-5.
doi: 10.1128/AAC.36.11.2533.

Increasing resistance of enterococci to ciprofloxacin

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Comparative Study

Increasing resistance of enterococci to ciprofloxacin

D R Schaberg et al. Antimicrob Agents Chemother. 1992 Nov.

Abstract

We determined that resistance to ciprofloxacin has emerged in enterococci over the last 5 years in our hospital, mainly in strains demonstrating the phenotype of high-level gentamicin resistance. All high-level-gentamicin-resistant isolates from 1985 and 1986 were susceptible, whereas 24% of isolates from 1989 and 1990 were resistant to ciprofloxacin. Plasmid and genomic DNA typing showed at least six unique strains exhibiting resistance, but one type accounted for 80% of recent resistant isolates, suggesting a role for cross infection in the emergence of resistance.

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