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. 1992;32(6):305-7.
doi: 10.1159/000116849.

Lamotrigine as an add-on drug in the management of Lennox-Gastaut syndrome

P L Timmings  1 , A Richens
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Lamotrigine as an add-on drug in the management of Lennox-Gastaut syndrome

P L Timmings et al. Eur Neurol. 1992.

Abstract

We report our experience with lamotrigine add-on therapy in the treatment of 11 patients with Lennox-Gastaut syndrome. Lamotrigine is a novel antiepileptic drug, chemically unrelated to the major anticonvulsants in current use. Ten patients experienced a > 50% reduction in seizure frequency, 1 patient experienced no change in seizure frequency. All patients tolerated lamotrigine satisfactorily and no side-effects were reported.

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