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Review
. 1992 Dec;8(12):427-32.
doi: 10.1016/0168-9525(92)90326-y.

Chromatin diminution in nematode development

H Tobler  1 , A Etter, F Müller
Affiliations
Review

Chromatin diminution in nematode development

H Tobler et al. Trends Genet. 1992 Dec.

Abstract

Chromatin diminution in Parascaris and Ascaris represents the classical case of a developmentally programmed genome rearrangement. The process is very specific with respect to ontogenetic timing and chromosomal localization, and involves chromosomal breakage, new telomere formation and DNA degradation. Recent evidence from Ascaris lumbricoides var. suum suggests that chromatin diminution might have a function in gene regulation.

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