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Case Reports
. 2004 Jan-Feb;14(1):67-8.

Transverse leukonychia in severe hypocalcemia

Caterina Foti  1 , Nicoletta Cassano, Vincenzo O Palmieri, Piero Portincasa, Anna Conserva, Michele Lamuraglia, Giuseppe Palasciano, Gino A Vena
Affiliations
  • PMID: 14965801
Case Reports

Transverse leukonychia in severe hypocalcemia

Caterina Foti et al. Eur J Dermatol. 2004 Jan-Feb.

Abstract

We report the case of a 26-year-old man with acral tetany and muscular cramps of the upper limbs associated with hypocalcemia caused by hypoparathyroidism and celiac disease. Physical examination revealed a transverse leukonychia which disappeared after treatment with calcium lactogluconate, calcium carbonate and calcitriol. Hypocalcemia may induce nail alterations with a double mechanism represented by angiospasm and disorganization of the hard keratin and of the integrin subunits.

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