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Case Reports
. 1978 Jun;38(6):422-30.

[Prenatal diagnosis in pregnancies at advanced maternal age (author's transl)]

[Article in German]
A Wirtz, B Haas, C Krauss, S Stengel-Rutkowski, J D Murken
  • PMID: 149691
Case Reports

[Prenatal diagnosis in pregnancies at advanced maternal age (author's transl)]

[Article in German]
A Wirtz et al. Geburtshilfe Frauenheilkd. 1978 Jun.

Abstract

Among 113 prenatal diagnoses in pregnancies at advanced maternal age (mothers older than 37 years) 7 aberrant fetal karyotypes were found (6.2%). Detailed reports of one case of trisomy 21, 18 and 13 each, as well as of XXY-, XYY- and XXX gonosomal constitution respectively are presented in the following. The frequency and severity of chromosome aberrations occurring in fetuses from elder women are discussed with respect to data from the literature. It seems that this group bears a higher risk for chromosomally abnormal offspring than has been suggested before.

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