doi: 10.1002/gepi.1370010216.
Genetic Analysis Workshop II: multiple-locus segregation analysis incorporating linkage markers
Affiliations
- PMID: 14971378
- DOI: 10.1002/gepi.1370010216
Item in Clipboard
Genetic Analysis Workshop II: multiple-locus segregation analysis incorporating linkage markers
Genet Epidemiol.
1984.
Abstract
The workshop data were examined using a newly developed methodology (MILINK, Risch, 1984) for combined segregation, linkage, and association analysis of a complex disease trait in pedigree data. Results from problems two and three suggest that the method is powerful both for determining mode of disease inheritance and for resolution of linkage disequilibrium versus pleiotrophy (with epistasis) of marker alleles.
Similar articles
-
Genetic Analysis Workshop II: further consideration of segregation and linkage analyses in Problem 3.Genet Epidemiol. 1984;1(2):189-93. doi: 10.1002/gepi.1370010213. Genet Epidemiol. 1984. PMID: 14971372
-
Genetic Analysis Workshop II: segregation and linkage analysis.Genet Epidemiol. 1984;1(2):201-5. doi: 10.1002/gepi.1370010215. Genet Epidemiol. 1984. PMID: 14971376
-
Genetic Analysis Workshop II: combined segregation, linkage, and association analysis.Genet Epidemiol. 1984;1(2):195-9. doi: 10.1002/gepi.1370010214. Genet Epidemiol. 1984. PMID: 14971374
-
On selecting markers for association studies: patterns of linkage disequilibrium between two and three diallelic loci.Genet Epidemiol. 2003 Jan;24(1):57-67. doi: 10.1002/gepi.10217. Genet Epidemiol. 2003. PMID: 12508256 Review.
-
Adaptation of the extended transmission/disequilibrium test to distinguish disease associations of multiple loci: the Conditional Extended Transmission/Disequilibrium Test.Ann Hum Genet. 2000 May;64(Pt 3):207-13. doi: 10.1017/S0003480000008095. Ann Hum Genet. 2000. PMID: 11246472 Review.
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
