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. 2004 Jan 5;318(1):102-11.
doi: 10.1016/j.virol.2003.09.025.

Herpesvirus of turkeys: microarray analysis of host gene responses to infection

Gamze Karaca  1 , Jonathan Anobile, Danielle Downs, Joan Burnside, Carl J Schmidt
Affiliations
Free article

Herpesvirus of turkeys: microarray analysis of host gene responses to infection

Gamze Karaca et al. Virology. .
Free article

Erratum in

  • Virology. 2015 Dec;486():1

Abstract

Herpesvirus of turkeys (HVT) provides an economically important live vaccine for prevention of Marek's disease (MD) of chickens. MD, characterized by both immunosuppression and T-cell lymphoma, is caused by another herpesvirus termed Marek's disease virus (MDV). Microarrays were used to investigate the response of chicken embryonic fibroblasts (CEF) to infection with HVT. Genes responding to HVT infection include several induced by interferon along with others modulating signal transduction, transcription, scaffolding proteins, and the cytoskeleton. Results are compared with earlier studies examining the responses of CEF cells to infection with MDV.

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