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Review
. 2004 Feb 21;328(7437):447-51.
doi: 10.1136/bmj.328.7437.447.

How strong is the evidence of a link between environmental chemicals and adverse effects on human reproductive health?

Richard M Sharpe  1 , D Stewart Irvine
Affiliations
Review

How strong is the evidence of a link between environmental chemicals and adverse effects on human reproductive health?

Richard M Sharpe et al. BMJ. .
No abstract available

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Figures

Fig 1
Fig 1
Potential pathways of endocrine disruption by environmental chemicals. DDE=1,1-dichloro-2, 2-bis(p-chlorophenyl)ethylene; PAHs=polycyclic aromatic hydrocarbons; PCBs=polychlorinated biphenyls; TBT=tributyltin
Fig 2
Fig 2
Trends in reproductive health, United States (for data sources see bmj.com)
Fig 3
Fig 3
Routes of human exposure to some common environmental chemicals. DDE=1,1-dichloro-2, 2-bis(p-chlorophenyl)ethylene, DDT=dichlorodiphenyltrichloroethane, PAHs=polycyclic aromatic hydrocarbons, PCBs=polychlorinated biphenyls
See this image and copyright information in PMC

References

    1. Damstra T, Barlow S, Bergman A, Kavlock R, Van Der Kraak G, eds. Global assessment of the state-of-the-science of endocrine disruptors. International Programme on Chemical Safety, 2002. http://ehp.niehs.nih.gov/who/ (accessed 3 Feb 2004).
    1. Czene K, Lichtenstein P, Hemminki K. Environmental and heritable causes of cancer among 9.6 million individuals in the Swedish family-cancer database. Int J Cancer 2002;99: 260-6. - PubMed
    1. Jeyaratnam J. Acute pesticide poisoning: a major global health problem. World Health Stat Q 1990;43: 139-44. - PubMed
    1. Second Health and Nutrition Examination Survey (NHANES). Report on human exposure to environmental chemicals. Atlanta: National Center for Environmental Health, 2003. (Publication No 02-0716.) www.cdc.gov/nceh/dls/report/ (accessed 3 Feb 2003).
    1. Mylchreest E, Sar M, Cattley R, Foster PMD. Disruption of androgen-regulated male reproductive development by di(n-butyl) phthalate during late gestation in rats is different from flutamide. Toxicol Appl Pharmacol 1999;156: 81-95. - PubMed

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