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. 2003;48(5):649-53.
doi: 10.1007/BF02993473.

The effects of magnesium, calcium and EDTA on slime production by Staphylococcus epidermidis strains

N Ozerdem Akpolat  1 , S Elçi, S Atmaca, H Akbayin, K Gül
Affiliations

The effects of magnesium, calcium and EDTA on slime production by Staphylococcus epidermidis strains

N Ozerdem Akpolat et al. Folia Microbiol (Praha). 2003.

Abstract

Effect of magnesium, calcium and EDTA on slime production by 15 slime-positive and 13 slime-negative Staphylococcus epidermidis strains isolated from various clinical specimens was determined. The slime production on tryptic soy broth was significantly enhanced after addition of 128 mumol/L Mg2+. Similarly, the addition of Ca2+ caused a significant increase in slime production of all tested strains when concentration of Ca2+ exceeded 64 mumol/L. In contrast, in the presence of EDTA the slime production by all strains was significantly reduced. Hence Ca2+ and Mg2+ increase slime production of S. epidermidis. This finding is important in the context of the pathogenesis of biomedical implant infections caused by S. epidermidis.

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