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Clinical Trial
. 2004 Jan-Feb;28(1):72-86.
doi: 10.5993/ajhb.28.1.8.

Comparative testing of 5 nicotine systems: initial use and preferences

Nina G Schneider  1 , Richard E Olmstead, Mitchell Nides, Freny Vaghaiwalla Mody, Pamela Otte-Colquette, Kim Doan, Shilpan Patel
Affiliations
Clinical Trial

Comparative testing of 5 nicotine systems: initial use and preferences

Nina G Schneider et al. Am J Health Behav. 2004 Jan-Feb.

Abstract

Objective: To test initial reactions to 5 nicotine treatments (NRTs: 2 and 4 mg gum, inhaler, nasal spray, tablet) in a crossover study (n=41).

Methods: Subjects used each medication on arising (1/2 day) and resumed smoking each afternoon. Subjects rated (individually) and ranked (comparatively) treatments on use, reinforcement, withdrawal, craving, and preferences.

Results: Overall preferences: inhaler (49%), 4 mg gum (24%), 2 mg gum (10%), 2 mg tablet (10%), nasal spray (7%). Overall results were consistent with ratings and rankings of individual characteristics of drugs.

Conclusion: Subjects had varied reactions to NRTs that may affect initiation of cessation.

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