Sepsis associated encephalopathy (SAE): a review
- PMID: 14977574
- DOI: 10.2741/1250
Sepsis associated encephalopathy (SAE): a review
Abstract
Sepsis associated encephalopathy (SAE) is a poorly understood condition that is associated with severe sepsis and appears to have a negative influence on survival. The incidence of encephalopathy secondary to sepsis is unknown. Amino acid derangements, blood-brain barrier disruption, abnormal neurotransmitters, and direct CNS effect are possible causes of septic encephalopathy. Research has not defined the pathogenesis of SAE.
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