Antibody response in sows and piglets following vaccination against Mycoplasma hyopneumoniae, toxigenic Pasteurella multocida, and Actinobacillus pleuropneumoniae
- PMID: 14979438
- PMCID: PMC1142132
Antibody response in sows and piglets following vaccination against Mycoplasma hyopneumoniae, toxigenic Pasteurella multocida, and Actinobacillus pleuropneumoniae
Abstract
The aim of the experimental study was to compare the humoral immune response and occurrence of adverse effects following single or multiple simultaneous vaccination of sows against Mycoplasma hyopneumonia, toxigenic Pasteurella multocida, and Actinobacillus pleuropneumoniae. In addition, passively transferred antibodies to piglets were studied until weaning at 3 weeks of age. Fever was seen in a few sows within the first 12 hours after the 1st and 2nd vaccination. No difference in the occurrence of other adverse effects was observed between groups. Antibody levels were significantly higher in vaccinated sows and their offspring compared with the control group. This was found to be independent of single or simultaneous vaccinations with the 3 vaccines. In conclusion, applying multiple vaccines simultaneously to sows appeared not to influence the occurrence of adverse effects or the sow's serum levels of antibodies at the time of farrowing, nor the offspring's serum levels up to 3 weeks of age.
Le but de cette étude expérimentale était de comparer la réponse immunitaire humorale et l’apparition d’effets indésirables suivant la vaccination unique ou multiple de truies avec Mycoplasma hyopneumoniae, Pasteurella multocida toxinogène et Actinobacillus pleuropneumoniae. De plus, on évalua les anticorps transmis passivement aux porcelets jusqu’au moment du sevrage à 3 semaines d’âge. De la fièvre a été notée chez quelques truies dans les 12 premières heures suivant la 1ère et 2e vaccination. Aucune différence dans l’apparition d’autres effets adverses n’a été observée entre les groupes. Les titres d’anticorps étaient plus élevés de manière significative chez les truies vaccinées et leurs rejetons comparativement au groupe témoin. Ce phénomène était indépendant d’une vaccination unique ou multiple avec les 3 vaccins. En conclusion, une vaccination simultanée multiple des truies ne semble pas influencé l’apparition d’effets adverses, les titres d’anticorps sériques chez les truies au moment de la parturition, de même que les titres sériques chez les rejetons jusqu’à 3 semaines d’âge.
(Traduit par Docteur Serge Messier)
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