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Review
. 2004 Feb;10(1):53-62.
doi: 10.1177/1073858403260159.

Neuroenergetics: calling upon astrocytes to satisfy hungry neurons

Luc Pellerin  1 , Pierre J Magistretti
Affiliations
Review

Neuroenergetics: calling upon astrocytes to satisfy hungry neurons

Luc Pellerin et al. Neuroscientist. 2004 Feb.

Abstract

Classical neuroenergetics states that glucose is the exclusive energy substrate of brain cells and its full oxidation provides all the necessary energy to support brain function. Recent data have revealed a more intricate picture in which astrocytes play a key role in supplying lactate as an additional energy substrate in register with glutamatergic activity.

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