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Case Reports
. 2003 Sep-Oct;98(5):459-64.

[Infiltrating mucinous carcinoma developed on chronic anal fistula; diagnostic and surgical difficulties]

[Article in Romanian]
I N Mateş  1 , Daniela Dinu, Georgeta Rădulescu, Cristina Iosif
Affiliations
  • PMID: 14999975
Case Reports

[Infiltrating mucinous carcinoma developed on chronic anal fistula; diagnostic and surgical difficulties]

[Article in Romanian]
I N Mateş et al. Chirurgia (Bucur). 2003 Sep-Oct.

Abstract

Anal carcinoma is rare; fistula-in-ano is sometimes mentioned among other premalignant conditions. Chronic anal fistula is associated with malignant transformation to mucinous adenocarcinoma, difficult to diagnose in the anal region and associated to a poor prognosis. Malignant transformation to infiltrating colloid carcinoma was surprised during a one year period, in a patient with long-standing perianal fistula (24 years). Inflammatory changes of the perineal region and other peculiar characteristics (such as neoplastic spread following supurative pathways) were responsible for diagnostic and surgical difficulties.

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