Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2003 Dec;35(6):461-75.
doi: 10.1023/b:jobb.0000008020.86004.28.

Calcium channels: unanswered questions

Stephen W Jones  1
Affiliations
Review

Calcium channels: unanswered questions

Stephen W Jones. J Bioenerg Biomembr. 2003 Dec.

Abstract

Despite decades of intensive research, many questions remain unresolved regarding the structure and function of voltage-dependent calcium channels. This review considers some of those questions: Where is the activation gate? Where are the inactivation gates? How are the voltage sensors coupled to the gates? Are bacterial K+ channels good models for the Ca2+ channel pore? Are protein-protein interactions fundamental to Ca2+ channel function? Do voltage-dependent Ca2+ channels regulate basal intracellular Ca2+? Are N and P/Q channels specialized for fast neurotransmitter release?

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Neuron. 2000 Mar;25(3):533-5 - PubMed
    1. Proc Natl Acad Sci U S A. 1997 Mar 4;94(5):1703-8 - PubMed
    1. Cell. 2002 Mar 8;108(5):595-8 - PubMed
    1. Biophys J. 1981 Mar;33(3):289-321 - PubMed
    1. J Neurosci. 2001 Aug 15;21(16):5944-51 - PubMed

Publication types

LinkOut - more resources