Mersacidin, a new antibiotic from Bacillus. Fermentation, isolation, purification and chemical characterization
- PMID: 1500347
- DOI: 10.7164/antibiotics.45.832
Mersacidin, a new antibiotic from Bacillus. Fermentation, isolation, purification and chemical characterization
Abstract
Mersacidin (1) is a new peptide antibiotic containing beta-methyllanthionine. It is classified as a member of the proposed lantibiotic group of antibiotics, and is produced by a species of Bacillus. Mersacidin has a molecular weight of 1,824 (C80H120N20O21S4). The antibiotic is active against Gram-positive organisms including methicillin-resistant Staphylococcus aureus, but has no activity against Gram-negative bacteria or fungi.
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