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. 2004 Mar;42(3):1356-9.
doi: 10.1128/JCM.42.3.1356-1359.2004.

Cryptococcus neoformans shows a remarkable genotypic diversity in Brazil

M T Barreto de Oliveira  1 , T Boekhout, B Theelen, F Hagen, F A Baroni, M S Lazera, K B Lengeler, J Heitman, I N G Rivera, C R Paula
Affiliations

Cryptococcus neoformans shows a remarkable genotypic diversity in Brazil

M T Barreto de Oliveira et al. J Clin Microbiol. 2004 Mar.

Abstract

The genotypic diversity of Brazilian Cryptococcus neoformans strains was analyzed. The majority of the samples were alphaA (65%), followed by alphaB (17.5%), alphaD (9%), alphaAaD hybrids (5%), and alphaC (3.5%). A considerable genotypic diversity occurred within C. neoformans var. grubii, and a new amplified fragment length polymorphism genotype, 1B, was recognized.

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Figures

FIG. 1.
FIG. 1.
Clustering of AFLP banding patterns of Brazilian isolates of C. neoformans and C. gattii (C. bacillisporus). (ICB 102 was demonstrated to represent Cryptococcus diffluens.). The new AFLP genotype, 1B, is indicated in boldface.
FIG. 2.
FIG. 2.
AFLP patterns of AFLP genotypes 1, 1A, and 1B showing the presence of genetic markers co-occurring in all pairs of these genotypes. Isolates 125.91, RV64610, RV65662, HamdanC3′1, Hamdan229, and RV58146 were included as a reference. The numbers given at the branches represent the cophenetic values.
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