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. 2004 Mar 5;116(5):633-4.
doi: 10.1016/s0092-8674(04)00209-0.

Visualizing gene expression: an unfolding story

Steven Henikoff  1
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Free article
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Visualizing gene expression: an unfolding story

Steven Henikoff. Cell. .
Free article

Abstract

Eukaryotic transcription is a dynamic process in which RNA polymerases read DNA templates that are tightly wrapped around histones. In this issue of Cell, Janicki et al. (2004) provide a glimpse of the events that follow transcriptional induction, using an integrated cytological system observed in real time. They find that local decondensation of the template is accompanied by profound changes in chromatin composition.

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