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Multicenter Study
. 2004 Apr;92(6):518-9.
doi: 10.1007/s00436-004-1069-9. Epub 2004 Mar 9.

Performance of an immunochromatographic test for the rapid diagnosis of malaria

Joachim Richter  1 , Gundel Harms, Irmela Müller-Stöver, Klaus Göbels, Dieter Häussinger
Affiliations
Multicenter Study

Performance of an immunochromatographic test for the rapid diagnosis of malaria

Joachim Richter et al. Parasitol Res. 2004 Apr.

Abstract

The immunochromatographic test (ICT) for the rapid diagnosis of malaria has been marketed for several years. In a study in which three Centres of Tropical Medicine participated and data were pooled, performance of the test varied considerably when comparing the results between each centre. The sensitivity of ICT in 2,343 patients tested in our services was 100% and the specificity 99.74%. Moreover, two patients with a positive ICT would initially have been missed by expert microscopy, with Plasmodium falciparum malaria being confirmed microscopically some hours later. The principal reasons for the better performance of the test in our series appear to be blood collection in EDTA vials and considerable experience with handling and interpreting the ICT test.

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References

    1. Scand J Infect Dis. 2001;33(10):752-4 - PubMed
    1. Parasitol Res. 2003 Mar;89(5):354-7 - PubMed

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