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Case Reports
. 2004 Apr;23(4):340-1.
doi: 10.1007/s10096-004-1106-8. Epub 2004 Mar 6.

Use of intravenous polymyxin B during continuous venovenous hemodialysis

J C Sarria  1 , F Angulo-Pernett, R C Kimbrough, C S McVay, A M Vidal
Affiliations
Case Reports

Use of intravenous polymyxin B during continuous venovenous hemodialysis

J C Sarria et al. Eur J Clin Microbiol Infect Dis. 2004 Apr.

Abstract

Described here is the case of a 23-year-old male with Acinetobacter baumannii sepsis and acute renal failure requiring continuous venovenous hemodialysis treated successfully with intravenous polymyxin B. The drug was administered as a loading dose of 2.5 mg/kg, followed by 2 doses of 1 mg/kg on days 4 and 8, then 0.8 mg/kg daily to complete a 24-day course. A discussion of dosing recommendations for polymyxins in dialysis is presented.

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