Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2004 Mar 17;126(10):3070-1.
doi: 10.1021/ja0496468.

Metallophosphites as umpolung catalysts: the enantioselective cross silyl benzoin reaction

Xin Linghu  1 , Justin R Potnick, Jeffrey S Johnson
Affiliations

Metallophosphites as umpolung catalysts: the enantioselective cross silyl benzoin reaction

Xin Linghu et al. J Am Chem Soc. .

Abstract

Carbonyl polarity reversal (umpolung) has been realized employing metallophosphites as catalysts. As a result, nonenzymatic asymmetric cross silyl benzoin reactions have been achieved, giving optically active silyl ether-protected benzoin adducts. The reaction is general with respect to aryl, alkyl, and heterocyclic substrates with good to excellent yields and good to excellent enantioselectivities.

PubMed Disclaimer

LinkOut - more resources