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. 1992 Sep;66(9):5631-4.
doi: 10.1128/JVI.66.9.5631-5634.1992.

Interactions of HTF4 with E-box motifs in the long terminal repeat of human immunodeficiency virus type 1

Y Zhang  1 , K Doyle, M Bina
Affiliations

Interactions of HTF4 with E-box motifs in the long terminal repeat of human immunodeficiency virus type 1

Y Zhang et al. J Virol. 1992 Sep.

Abstract

We have identified three consensus E-box motifs in the long terminal repeat of human immunodeficiency virus type 1. One of these E boxes interacts selectively with representative members of the class A group of basic helix-loop-helix proteins, including HTF4, E47, and their heterodimers. Our analyses implicate the helix-loop-helix proteins in regulation of human immunodeficiency virus type 1 gene expression.

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