Can the clock be turned back on ovarian aging?
- PMID: 15014203
- DOI: 10.1126/sageke.2004.10.pe11
Can the clock be turned back on ovarian aging?
Abstract
A basic tenet of reproductive biology is that female mammals are born with a set number of germ cells (oocytes). A new study by Johnson et al. challenges these beliefs by demonstrating that the postnatal mouse ovary contains actively dividing germ cells. These findings have implications for prolonging the reproductive life span of women.
Similar articles
-
Aging of oocyte, ovary, and human reproduction.Ann N Y Acad Sci. 2004 Dec;1034:117-31. doi: 10.1196/annals.1335.015. Ann N Y Acad Sci. 2004. PMID: 15731305 Review.
-
[Is neo-oogenesis in the adult ovary, a realistic paradigm?].Gynecol Obstet Fertil. 2010 Jun;38(6):398-401. doi: 10.1016/j.gyobfe.2010.04.013. Epub 2010 Jun 4. Gynecol Obstet Fertil. 2010. PMID: 20576550 Review. French.
-
Stem cells and fertility: what does the future hold?Curr Opin Obstet Gynecol. 2006 Jun;18(3):338-43. doi: 10.1097/01.gco.0000193008.88652.23. Curr Opin Obstet Gynecol. 2006. PMID: 16735836 Review.
-
[Neo-oogenesis, possibility of oryjgin of oocytes and primordial ovarian follicles in postnatal period in women].Folia Med Cracov. 2007;48(1-4):91-7. Folia Med Cracov. 2007. PMID: 19051696 Review. Polish.
-
[Neo-oogenesis in the postnatal ovary: fantasy or reality?].Gynecol Obstet Fertil. 2005 Oct;33(10):819-23. doi: 10.1016/j.gyobfe.2005.07.029. Gynecol Obstet Fertil. 2005. PMID: 16139541 Review. French.
Cited by
-
An evolutionary perspective on adult female germline stem cell function from flies to humans.Semin Reprod Med. 2013 Jan;31(1):24-32. doi: 10.1055/s-0032-1331794. Epub 2013 Jan 17. Semin Reprod Med. 2013. PMID: 23329633 Free PMC article. Review.
-
High fat diet induced obesity alters ovarian phosphatidylinositol-3 kinase signaling gene expression.Reprod Toxicol. 2013 Dec;42:68-77. doi: 10.1016/j.reprotox.2013.07.026. Epub 2013 Aug 14. Reprod Toxicol. 2013. PMID: 23954404 Free PMC article.
-
Nonproliferative and proliferative lesions of the rat and mouse female reproductive system.J Toxicol Pathol. 2014;27(3-4 Suppl):1S-107S. doi: 10.1293/tox.27.1S. J Toxicol Pathol. 2014. PMID: 25516636 Free PMC article. Review.
-
The current status of evidence for and against postnatal oogenesis in mammals: a case of ovarian optimism versus pessimism?Biol Reprod. 2009 Jan;80(1):2-12. doi: 10.1095/biolreprod.108.069088. Epub 2008 Aug 27. Biol Reprod. 2009. PMID: 18753611 Free PMC article. Review.
-
Impact of obesity on ovotoxicity induced by 7,12-dimethylbenz[a]anthracene in mice.Biol Reprod. 2014 Mar 27;90(3):68. doi: 10.1095/biolreprod.113.114215. Print 2014 Mar. Biol Reprod. 2014. PMID: 24501177 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical