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. 2000 Jun;2(3):80-88.
doi: 10.4088/pcc.v02n0302.

Novel Antipsychotics in the Treatment of Behavioral Disturbances and Psychoses Associated With Neurodegenerative Disorders

Prakash S. Masand  1
Affiliations

Novel Antipsychotics in the Treatment of Behavioral Disturbances and Psychoses Associated With Neurodegenerative Disorders

Prakash S. Masand. Prim Care Companion J Clin Psychiatry. 2000 Jun.

Abstract

Behavioral disturbances and psychosis are common features of neurodegenerative disorders and may be drug induced, intrinsic to the underlying pathology, or both. These disturbances, including psychotic and mood symptoms, apathy, aggression and other behavioral symptoms, and superimposed delirium, cause a great amount of disability to the patient and stress on the caregiver. Conventional neuroleptics have been shown to be effective in the treatment of these symptoms, but unacceptable side effects may occur. However, the novel antipsychotics, with their lower risk of inducing extrapyramidal symptoms, have shown promise in the treatment of behavioral disturbances and psychosis associated with neurodegenerative disorders.

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References

    1. Masand PS. Using newer antipsychotic agents in primary care. Prim Psychiatry. 1997;4:64–68.
    1. Jeste DV, McClure FS. Psychoses: diagnosis and treatment in the elderly. New Dir Ment Health Serv. 1997;(76):53–70. - PubMed
    1. Lacro JP, Jeste DV. Geriatric psychosis. Psychiatr Q. 1997;68:247–260. - PubMed
    1. Tariot PN, Blazina L. The psychopathology of dementia. In: Morris JC, ed. Handbook of Dementing Illnesses. New York, NY: Marcel Dekker. 1994 461–475.
    1. Devanand J, Levy SR. Neuroleptic treatment of agitation and psychosis in dementia. J Geriatr Psychiatry Neurol. 1995;8:18–27. - PubMed