Pulling back to move forward
- PMID: 15016370
- DOI: 10.1016/s0092-8674(04)00123-0
Pulling back to move forward
Abstract
Animal cells can change shape and move by using actin polymerization to drive plasma membrane protrusion. Giannone and coworkers (this issue of Cell) describe how cells periodically pull back on these protrusions in order to sense and respond to the rigidity of their environment.
Comment on
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Periodic lamellipodial contractions correlate with rearward actin waves.Cell. 2004 Feb 6;116(3):431-43. doi: 10.1016/s0092-8674(04)00058-3. Cell. 2004. PMID: 15016377
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