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Comment
. 2004 Apr;53(4):475-7.
doi: 10.1136/gut.2003.025155.

Fatigue in chronic cholestasis

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Comment

Fatigue in chronic cholestasis

P Milkiewicz et al. Gut. 2004 Apr.

Abstract

Fatigue is probably the most intriguing symptom affecting patients with chronic cholestatic disorders, in particular those with primary biliary cirrhosis. It is postulated that fatigue in patients with primary biliary cirrhosis may be associated with morphological abnormalities of the central nervous system secondary to accumulation of manganese. However, we are still far from understanding this complex issue.

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  • Fatigue in primary biliary cirrhosis.
    Forton DM, Patel N, Oatridge A, Hamilton G, Hajnal JV, Thomas HC, Taylor-Robinson SD, Prince M, Goldblatt J, Bassendine M, Jones DE. Forton DM, et al. Gut. 2005 Mar;54(3):438. doi: 10.1136/gut.2004.046763. Gut. 2005. PMID: 15710997 Free PMC article. No abstract available.

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References

    1. Stedman’s Medical Dictionary, 25 edn. Baltimore: Williams & Wilkins, 1990.
    1. Bakshi R. Fatigue associated with multiple sclerosis: diagnosis, impact and management. Mult Scler 2003;9:219–27. - PubMed
    1. Omdal R, Waterloo K, Koldingsnes W, et al. Fatigue in patients with systemic lupus erythematosus: the psychosocial aspects. J Rheumatol 2003;30:283–7. - PubMed
    1. Jones EA. Fatigue associated with chronic liver disease: a riddle wrapped in a mystery inside an enigma. Hepatology 1995;22:1606–8. - PubMed
    1. Witt-Sullivan H, Heathcote EJL, Cauch K, et al. The demography of primary biliary cirrhosis in Ontario, Canada. Hepatology 1990;12:98–105. - PubMed