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. 2004 Feb;111(2):244-9.
doi: 10.1016/j.ophtha.2003.09.024.

Risk factors for central serous chorioretinopathy: a case-control study

Robert Haimovici  1 , Sean Koh, David R Gagnon, Todd Lehrfeld, Sarah Wellik; Central Serous Chorioretinopathy Case-Control Study Group
Affiliations

Risk factors for central serous chorioretinopathy: a case-control study

Robert Haimovici et al. Ophthalmology. 2004 Feb.

Abstract

Purpose: To identify systemic factors associated with the development of central serous chorioretinopathy (CSCR).

Design: Retrospective, case-control study.

Participants and controls: 312 cases and 312 controls.

Results: By use of a multivariate analysis, the previously described risk factors, systemic steroid use (odds ratio [OR], 37.1; 95% confidence interval [CI], 6.2-221.8), and pregnancy (OR, 7.1; 95% CI, 1.0-50.7), were strongly associated with CSCR. Additional risk factors identified by this study include antibiotic use (OR, 6.2; 95% CI, 1.0-37.9), alcohol use (OR, 4.9; 95% CI, 1.5-16.3), untreated hypertension (OR, 3.3; 95% CI, 1.3-8.5), and allergic respiratory disease (OR, 2.5; 95% CI, 1.2-5.1).

Conclusions: A wide variety of systemic factors are associated with CSCR. Prospective studies are warranted to evaluate the nature and significance of these associations further.

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