Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2004 Feb;10(2):207-9.
doi: 10.3201/eid1002.030426.

Multiple contact dates and SARS incubation periods

Affiliations

Multiple contact dates and SARS incubation periods

Martin I Meltzer. Emerg Infect Dis. 2004 Feb.

Abstract

Many severe acute respiratory syndrome (SARS) patients have multiple possible incubation periods due to multiple contact dates. Multiple contact dates cannot be used in standard statistical analytic techniques, however. I present a simple spreadsheet-based method that uses multiple contact dates to calculate the possible incubation periods of SARS.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Simulation of frequency distribution of incubation period of severe acute respiratory syndrome. Data used for this simulation were obtained from Canada (6), Hong Kong (7), and the United States, for a total sample size of 19. Many of the patients included in the database had multiple possible incubation periods (see Table), resulting in the confidence intervals displayed for each day.
Figure 2
Figure 2
Cumulative frequency incubation period of severe acute respiratory syndrome. Data are the mean frequencies of each individual incubation period, as shown in Figure 1. Data used for this simulation were obtained from Canada (6), Hong Kong (7), and the United States, for a sample size 19. Many of the patients included in the database had multiple possible incubation periods (see Table).

Comment in

  • Estimating SARS incubation period.
    Wong TW, Tam W. Wong TW, et al. Emerg Infect Dis. 2004 Aug;10(8):1503-4; author reply 1504. doi: 10.3201/eid1008.040284. Emerg Infect Dis. 2004. PMID: 15503397 Free PMC article. No abstract available.

References

    1. Peiris JSM, Lai ST, Poon LLM, Guan Y, Yam LYC, Lim W, et al. Coronavirus as a possible cause of severe acute respiratory syndrome. Lancet. 2003;361:1319–25. 10.1016/S0140-6736(03)13077-2 - DOI - PMC - PubMed
    1. Ksiazek TG, Erdman D, Goldsmith CS, Zaki SR, Peret T, Emery S, et al. A novel coronavirus associated with severe acute respiratory syndrome. N Engl J Med. 2003;348:1953–66. 10.1056/NEJMoa030781 - DOI - PubMed
    1. Drosten C, Günther S, Preiser W, van der Werf S, Brodt H-R, Becker S, et al. Identification of a novel coronavirus in patients with severe acute respiratory syndrome. N Engl J Med. 2003;348:1967–76. 10.1056/NEJMoa030747 - DOI - PubMed
    1. Chew P, Coughlin P, Chambers J. S&P correct: respiratory disease SARS chokes Asia-Pacific growth, but sovereign ratings are secure. [Accessed April 29, 2003] Available from: URL: http://www.standardandpoors.com
    1. Special report: the SARS epidemic. The Economist 2003, April 26;367:18–20.

MeSH terms

LinkOut - more resources