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Comparative Study
. 2004 Mar;6(3):317-8.
doi: 10.1016/s1534-5807(04)00069-3.

Twist genes regulate Runx2 and bone formation

Henry M Kronenberg  1
Affiliations
Free article
Comparative Study

Twist genes regulate Runx2 and bone formation

Henry M Kronenberg. Dev Cell. 2004 Mar.
Free article

Abstract

Runx2, a master regulator of osteoblast differentiation, is expressed several days before osteoblast genes in bone anlage. In this issue of Developmental Cell, show that Twist-1 and Twist-2 suppress the activity of Runx2 and thereby regulate bone formation.

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