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. 2004 Apr;88(4):494-6.
doi: 10.1136/bjo.2003.027136.

A new form of retinopathy associated with myocardial infarction treated with percutaneous coronary intervention

N Kinoshita  1 , A Kakehashi, T Yasu, T Katayama, M Kuroki, Y Tsurimaki, R Ono, H Yamagami, M Saito, M Kawakami
Affiliations

A new form of retinopathy associated with myocardial infarction treated with percutaneous coronary intervention

N Kinoshita et al. Br J Ophthalmol. 2004 Apr.

Abstract

Aim: To report a new form of retinopathy that was observed in patients who had undergone percutaneous coronary intervention (PCI) following acute myocardial infarction (AMI).

Methods: Serial ophthalmological examinations were conducted in 40 patients who underwent PCI. Thirty patients were diagnosed with AMI, and another 10 had stable angina pectoris.

Results: Cotton wool spots developed in 17 (57%) patients from the group with AMI undergoing PCI (n = 30) within 2 months. Of these, 41% (seven patients) also developed superficial haemorrhages. Retinopathy was most prominent 1-2 months after AMI and then tended to become quiescent afterwards, without treatment.

Conclusion: We have identified a new form of retinopathy in patients with AMI that spontaneously subsides without treatment.

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Figures

Figure 1
Figure 1
Ophthalmological manifestations 1 month after AMI. Cotton wool spots and superficial haemorrhage are seen adjacent to the optic disc in the left eye (A). (B) Results of fluorescein angiography of the same eye. The arrow indicates a non-perfused area and overlying haemorrhage.
Figure 2
Figure 2
Time course of ophthalmic manifestations. Cotton wool spots were most frequently observed at 1 month and superficial haemorrhages at 2 months.
See this image and copyright information in PMC

References

    1. Destro M, Gragoudas ES. Arterial occlusions. In: Albert DM, Jakobiec FA, eds. Principle and practice of ophthalmology. Philadelphia: WB Saunders Company, 1994:727–8.
    1. Brown GC. Retinal arterial obstructive disease. In: Ryan SJ, ed. Retina. 2nd ed. St Louis, MO: Mosby-Year Book, Inc, 1994:1373–5.
    1. Brown GC, Brown MM, Hiller T, et al. Cotton wool spots. Retina 1985;5:206–14. - PubMed
    1. Teitelbaum BA. Asymptomatic unilateral microembolic retinopathy secondary to percutaneous transluminal coronary angioplasty. J Am Optom Assoc 1999;70:587–92. - PubMed
    1. Bucci FA Jr, Dimitsopulos TM, Krohel GB. Branch retinal artery occlusion secondary to percutaneous transluminal coronary angioplasty. Br J Ophthalmol 1989;73:309–10. - PMC - PubMed