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. 2004 Mar 19;303(5665):1810-3.
doi: 10.1126/science.1096800.

Organic chemistry in drug discovery

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Organic chemistry in drug discovery

Malcolm MacCoss et al. Science. .

Abstract

The role played by organic chemistry in the pharmaceutical industry continues to be one of the main drivers in the drug discovery process. However, the precise nature of that role is undergoing a visible change, not only because of the new synthetic methods and technologies now available to the synthetic and medicinal chemist, but also in several key areas, particularly in drug metabolism and chemical toxicology, as chemists deal with the ever more rapid turnaround of testing data that influences their day-to-day decisions.

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