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. 1992 Apr;36(4):886-9.
doi: 10.1128/AAC.36.4.886.

A pneumococcal clinical isolate with high-level resistance to cefotaxime and ceftriaxone

A M Figueiredo  1 , J D Connor, A Severin, M V Vaz Pato, A Tomasz
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A pneumococcal clinical isolate with high-level resistance to cefotaxime and ceftriaxone

A M Figueiredo et al. Antimicrob Agents Chemother. 1992 Apr.

Abstract

A beta-lactam-resistant serotype 23F Streptococcus pneumoniae clinical isolate from the cerebrospinal fluid of a pediatric patient from California is unusual in that the MICs of cefotaxime and ceftriaxone (2.5 micrograms/ml each) are higher than that of benzylpenicillin (0.3 micrograms/ml); the isolate also has patterns of penicillin-binding proteins and of cell wall peptides which are atypical compared with those of previously examined penicillin-resistant pneumococci.

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References

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