doi: 10.1128/AAC.36.4.886.
A pneumococcal clinical isolate with high-level resistance to cefotaxime and ceftriaxone
Affiliations
- PMID: 1503454
- PMCID: PMC189481
- DOI: 10.1128/AAC.36.4.886
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A pneumococcal clinical isolate with high-level resistance to cefotaxime and ceftriaxone
Antimicrob Agents Chemother.
1992 Apr.
Abstract
A beta-lactam-resistant serotype 23F Streptococcus pneumoniae clinical isolate from the cerebrospinal fluid of a pediatric patient from California is unusual in that the MICs of cefotaxime and ceftriaxone (2.5 micrograms/ml each) are higher than that of benzylpenicillin (0.3 micrograms/ml); the isolate also has patterns of penicillin-binding proteins and of cell wall peptides which are atypical compared with those of previously examined penicillin-resistant pneumococci.
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