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Review
. 1992 Jul;22(4):435-51.
doi: 10.1007/BF01066614.

Are paw preference differences in HI and LO mice the result of specific genes or of heterosis and fluctuating asymmetry?

I C McManus  1
Affiliations
Review

Are paw preference differences in HI and LO mice the result of specific genes or of heterosis and fluctuating asymmetry?

I C McManus. Behav Genet. 1992 Jul.

Abstract

Collins (1985) has described two separate mouse strains, obtained by selective breeding, which differ in having high (HI) or low (LO) degrees of paw preference on a standard test. In this paper I argue that the differences between these strains may not be due to a specific gene (or genes) but, instead, probably reflect differences in the total heterozygosity of the strains, such that the HI strain is more heterotic than the LO strain. Greater degrees of heterozygosity are argued to buffer against fluctuating asymmetry and hence result in a greater degree of paw preference.

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